New paper with the Boger group on 1,2,3-Triazine cycloadditions
Together with the Boger lab we recently published our work "Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and...
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Dennis Svatunek
- May 19, 2022
- 1 min
New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the
Our paper on the reactivity of 2-pyridyl tetrazines is now open access in JACS: https://pubs.acs.org/doi/10.1021/jacs.2c01056
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Dennis Svatunek
- Jul 4, 2021
- 1 min
New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines
In this collaborative work with Aneta Turlik and Ken Houk we investigated the increased Diels-Alder reactivity of tetrazines when...
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Dennis Svatunek
- Dec 30, 2020
- 1 min
New Preprint on the "Performance of Bioorthogonal Tetrazine Tools in Pretargeted in Vivo Chemistry"
Our work together with the Herth group and others is now available on the ChemRxiv.
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Dennis Svatunek
- Sep 18, 2020
- 1 min
Creating 2 Billion virtual compounds - new paper with the Harran group
Together with the Harran group (UCLA) we worked on a computational workflow to create a gigalibrary of composite peptidic macrocycles...
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Dennis Svatunek
- Sep 18, 2020
- 1 min
Poster at ARIT2020 awarded the Austrian Marshall Plan Foundation Poster Award!
My Poster and pitch about the "Rational Design of Bioorthogonal Reactants using Energy Decomposition Methods" was awarded the 3rd place...
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Dennis Svatunek
- Jul 10, 2020
- 1 min
Poster selected as 1 of 10 to be presented at the Austrian Research and Innovation Talks 2020
My poster was selected as one of 10 that will be presented at the Austrian Research and Innovation Talks (ARIT). The ARIT is virtual this...
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Dennis Svatunek
- Jul 3, 2020
- 1 min
I received the UCLA Chemistry and Biochemistry 2020 Postdoctoral Research Award
I am honored to receive the 2020 Postdoctoral Research Award of the UCLA Department of Chemistry and Biochemistry. I like to thank all my...
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Dennis Svatunek
- Jun 29, 2020
- 1 min
New paper in Polymer Chemistry: Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides
In this paper we describe the synthesis of tetrazine and trans-cyclooctene modified polypept(o)ides and their bioorthogonal reactivity....
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Dennis Svatunek
- May 1, 2020
- 1 min
Two articles awarded "Top Downloaded Article" by Wiley
Our articles "Factors Controlling the Diels–Alder Reactivity of Hetero‐1,3‐Butadienes" and "Elucidating the Trends in Reactivity of...
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![New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w](https://static.wixstatic.com/media/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png/v1/fill/w_454,h_266,fp_0.50_0.50,q_95,enc_auto/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png)
Dennis Svatunek
- Feb 14, 2020
- 1 min
New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w
We published a mechanistic study of the 2+2 and 4+2 cycloadditions between tetrafluorotheylene and butadiene. Read it here! (open access)
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Dennis Svatunek
- Jan 18, 2020
- 1 min
New paper: Live Monitoring of Strain‐Promoted Azide Alkyne Cycloadditions in Complex Reaction Enviro
We describe how ATR-IR can be used to follow strain-promoted azide alkyne cycloadditions even in biological solvent. Read this open...
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Dennis Svatunek
- Dec 11, 2019
- 1 min
New ACS nano paper: Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of
We demonstrate that PeptoBrushes can be used for pretargeted nuclear imaging. These PeptoBrushes also show unusual bioorthogonal...
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Dennis Svatunek
- Sep 27, 2019
- 1 min
Doing CompChem on PCs?
With the increase in computing power I'm wondering how much of (organic) computational chemistry could be done on a single PC. A short...
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Dennis Svatunek
- Sep 27, 2019
- 1 min
New article on new glycosyl donors for diastereoselective glycosylations published in Chemical Commu
This paper includes work I performed in my bachelor thesis. Great work by all authors! Link to paper (open access)
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Dennis Svatunek
- Sep 27, 2019
- 1 min
New article on tetrazine modified nanoparticles published in Biomacromolecules
Our paper together with the Zentel group at Johannes Gutenberg University Mainz is now available in Biomacromolecules. Great work by...
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Dennis Svatunek
- Sep 14, 2019
- 1 min
New paper: Isonitrile-responsive and Bioorthogonally Removable Tetrazine Protecting Groups
Together with the Franzini group we unraveled the mechanism of an accelerated release reaction in an isonitrile/tetrazine click to...
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Dennis Svatunek
- Jul 8, 2019
- 1 min
autoDIAS published in JCC
Our paper about our python tool for an automated Distortion/Interaction Activation Strain analysis is online in the Journal of...
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Dennis Svatunek
- Jul 5, 2019
- 1 min
Talk at Austrian Chemistry Days 2019
I will present research about bioorthogonal isonitrile/tetrazine reactions at the Österreichische Chemietage (Austrian Chemistry days) in...
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Dennis Svatunek
- Jul 1, 2019
- 1 min
NOS 2019 - poster presentation
Last week I attended NOS2019 at Indiana University in Bloomington, Indiana. A great meeting for networking and learning about science. I...
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