Personal Research Page | Dennis Svatunek

I am a computational chemist at TU Wien working on understanding and improving bioorthogonal cycloadditions and the development of new tools which provide better insight into reactivity and selectivity in organic reactions.

Tetrazine crystals

Phases

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New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the

Our paper on the reactivity of 2-pyridyl tetrazines is now open access in JACS: https://pubs.acs.org/doi/10.1021/jacs.2c01056

Jul 4, 2021

New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines

In this collaborative work with Aneta Turlik and Ken Houk we investigated the increased Diels-Alder reactivity of tetrazines when...

Dec 30, 2020

New Preprint on the "Performance of Bioorthogonal Tetrazine Tools in Pretargeted in Vivo Chemistry"

Our work together with the Herth group and others is now available on the ChemRxiv.

Sep 18, 2020

Creating 2 Billion virtual compounds - new paper with the Harran group

Together with the Harran group (UCLA) we worked on a computational workflow to create a gigalibrary of composite peptidic macrocycles...

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Recent News​

New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the

New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines

New Preprint on the "Performance of Bioorthogonal Tetrazine Tools in Pretargeted in Vivo Chemistry"

Creating 2 Billion virtual compounds - new paper with the Harran group

Recent News