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New paper with the Boger group on 1,2,3-Triazine cycloadditions

Together with the Boger lab we recently published our work "Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and 1,2,3,5-Tetrazines" in JACS. In this paper we investigate the mechanism of these cycloadditions using experimental (kinetic experiments, KIE, isotope labeling) and computational methods. We could show that these reactions proceed through an addition/elimination/electrocyclization mechanism. Find the open access paper here:

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