New paper with the Boger group on 1,2,3-Triazine cycloadditions
Together with the Boger lab we recently published our work "Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and...
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Dennis Svatunek
May 19, 20221 min read
New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the
Our paper on the reactivity of 2-pyridyl tetrazines is now open access in JACS: https://pubs.acs.org/doi/10.1021/jacs.2c01056
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Dennis Svatunek
Jul 4, 20211 min read
New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines
In this collaborative work with Aneta Turlik and Ken Houk we investigated the increased Diels-Alder reactivity of tetrazines when...
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Dennis Svatunek
Dec 30, 20201 min read
New Preprint on the "Performance of Bioorthogonal Tetrazine Tools in Pretargeted in Vivo Chemistry"
Our work together with the Herth group and others is now available on the ChemRxiv.
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Dennis Svatunek
Sep 18, 20201 min read
Creating 2 Billion virtual compounds - new paper with the Harran group
Together with the Harran group (UCLA) we worked on a computational workflow to create a gigalibrary of composite peptidic macrocycles...
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Dennis Svatunek
Sep 18, 20201 min read
Poster at ARIT2020 awarded the Austrian Marshall Plan Foundation Poster Award!
My Poster and pitch about the "Rational Design of Bioorthogonal Reactants using Energy Decomposition Methods" was awarded the 3rd place...
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Dennis Svatunek
Jul 10, 20201 min read
Poster selected as 1 of 10 to be presented at the Austrian Research and Innovation Talks 2020
My poster was selected as one of 10 that will be presented at the Austrian Research and Innovation Talks (ARIT). The ARIT is virtual this...
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Dennis Svatunek
Jul 3, 20201 min read
I received the UCLA Chemistry and Biochemistry 2020 Postdoctoral Research Award
I am honored to receive the 2020 Postdoctoral Research Award of the UCLA Department of Chemistry and Biochemistry. I like to thank all my...
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Dennis Svatunek
Jun 29, 20201 min read
New paper in Polymer Chemistry: Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides
In this paper we describe the synthesis of tetrazine and trans-cyclooctene modified polypept(o)ides and their bioorthogonal reactivity....
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Dennis Svatunek
May 1, 20201 min read
Two articles awarded "Top Downloaded Article" by Wiley
Our articles "Factors Controlling the Diels–Alder Reactivity of Hetero‐1,3‐Butadienes" and "Elucidating the Trends in Reactivity of...
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![New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w](https://static.wixstatic.com/media/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png/v1/fill/w_636,h_372,fp_0.50_0.50,lg_1,q_95,enc_auto/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png)
Dennis Svatunek
Feb 14, 20201 min read
New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w
We published a mechanistic study of the 2+2 and 4+2 cycloadditions between tetrafluorotheylene and butadiene. Read it here! (open access)
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Dennis Svatunek
Jan 18, 20201 min read
New paper: Live Monitoring of Strain‐Promoted Azide Alkyne Cycloadditions in Complex Reaction Enviro
We describe how ATR-IR can be used to follow strain-promoted azide alkyne cycloadditions even in biological solvent. Read this open...
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Dennis Svatunek
Dec 11, 20191 min read
New ACS nano paper: Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of
We demonstrate that PeptoBrushes can be used for pretargeted nuclear imaging. These PeptoBrushes also show unusual bioorthogonal...
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Dennis Svatunek
Sep 27, 20191 min read
New article on new glycosyl donors for diastereoselective glycosylations published in Chemical Commu
This paper includes work I performed in my bachelor thesis. Great work by all authors! Link to paper (open access)
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Dennis Svatunek
Sep 27, 20191 min read
New article on tetrazine modified nanoparticles published in Biomacromolecules
Our paper together with the Zentel group at Johannes Gutenberg University Mainz is now available in Biomacromolecules. Great work by...
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Dennis Svatunek
Sep 14, 20191 min read
New paper: Isonitrile-responsive and Bioorthogonally Removable Tetrazine Protecting Groups
Together with the Franzini group we unraveled the mechanism of an accelerated release reaction in an isonitrile/tetrazine click to...
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Dennis Svatunek
Jul 8, 20191 min read
autoDIAS published in JCC
Our paper about our python tool for an automated Distortion/Interaction Activation Strain analysis is online in the Journal of...
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Dennis Svatunek
Jul 5, 20191 min read
Talk at Austrian Chemistry Days 2019
I will present research about bioorthogonal isonitrile/tetrazine reactions at the Österreichische Chemietage (Austrian Chemistry days) in...
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Dennis Svatunek
Jul 1, 20191 min read
NOS 2019 - poster presentation
Last week I attended NOS2019 at Indiana University in Bloomington, Indiana. A great meeting for networking and learning about science. I...
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Dennis Svatunek
Jun 20, 20191 min read
Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonit
Our paper together with the Franzini group "Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with...
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