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    Dennis Svatunek

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    New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the
    Dennis Svatunek
    • May 19
    • 1 min

    New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the

    Our paper on the reactivity of 2-pyridyl tetrazines is now open access in JACS: https://pubs.acs.org/doi/10.1021/jacs.2c01056
    3 views0 comments
    New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines
    Dennis Svatunek
    • Jul 4, 2021
    • 1 min

    New preprint: Origin of Increased Reactivity in Rhenium-Mediated Cycloadditions of Tetrazines

    In this collaborative work with Aneta Turlik and Ken Houk we investigated the increased Diels-Alder reactivity of tetrazines when...
    14 views0 comments
    Dennis Svatunek
    • Dec 30, 2020
    • 1 min

    New Preprint on the "Performance of Bioorthogonal Tetrazine Tools in Pretargeted in Vivo Chemistry"

    Our work together with the Herth group and others is now available on the ChemRxiv.
    15 views0 comments
    Dennis Svatunek
    • Sep 18, 2020
    • 1 min

    Creating 2 Billion virtual compounds - new paper with the Harran group

    Together with the Harran group (UCLA) we worked on a computational workflow to create a gigalibrary of composite peptidic macrocycles...
    19 views0 comments
    Dennis Svatunek
    • Sep 18, 2020
    • 1 min

    Poster at ARIT2020 awarded the Austrian Marshall Plan Foundation Poster Award!

    My Poster and pitch about the "Rational Design of Bioorthogonal Reactants using Energy Decomposition Methods" was awarded the 3rd place...
    10 views0 comments
    Dennis Svatunek
    • Jul 10, 2020
    • 1 min

    Poster selected as 1 of 10 to be presented at the Austrian Research and Innovation Talks 2020

    My poster was selected as one of 10 that will be presented at the Austrian Research and Innovation Talks (ARIT). The ARIT is virtual this...
    10 views0 comments
    Dennis Svatunek
    • Jul 3, 2020
    • 1 min

    I received the UCLA Chemistry and Biochemistry 2020 Postdoctoral Research Award

    I am honored to receive the 2020 Postdoctoral Research Award of the UCLA Department of Chemistry and Biochemistry. I like to thank all my...
    17 views0 comments
    Dennis Svatunek
    • Jun 29, 2020
    • 1 min

    New paper in Polymer Chemistry: Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides

    In this paper we describe the synthesis of tetrazine and trans-cyclooctene modified polypept(o)ides and their bioorthogonal reactivity....
    4 views0 comments
    Dennis Svatunek
    • May 1, 2020
    • 1 min

    Two articles awarded "Top Downloaded Article" by Wiley

    Our articles "Factors Controlling the Diels–Alder Reactivity of Hetero‐1,3‐Butadienes" and "Elucidating the Trends in Reactivity of...
    7 views0 comments
    New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w
    Dennis Svatunek
    • Feb 14, 2020
    • 1 min

    New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w

    We published a mechanistic study of the 2+2 and 4+2 cycloadditions between tetrafluorotheylene and butadiene. Read it here! (open access)
    18 views0 comments
    New paper: Live Monitoring of Strain‐Promoted Azide Alkyne Cycloadditions in Complex Reaction Enviro
    Dennis Svatunek
    • Jan 18, 2020
    • 1 min

    New paper: Live Monitoring of Strain‐Promoted Azide Alkyne Cycloadditions in Complex Reaction Enviro

    We describe how ATR-IR can be used to follow strain-promoted azide alkyne cycloadditions even in biological solvent. Read this open...
    12 views0 comments
    New ACS nano paper: Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of
    Dennis Svatunek
    • Dec 11, 2019
    • 1 min

    New ACS nano paper: Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of

    We demonstrate that PeptoBrushes can be used for pretargeted nuclear imaging. These PeptoBrushes also show unusual bioorthogonal...
    13 views0 comments
    New article on new glycosyl donors for diastereoselective glycosylations published in Chemical Commu
    Dennis Svatunek
    • Sep 27, 2019
    • 1 min

    New article on new glycosyl donors for diastereoselective glycosylations published in Chemical Commu

    This paper includes work I performed in my bachelor thesis. Great work by all authors! Link to paper (open access)
    7 views0 comments
    New article on tetrazine modified nanoparticles published in Biomacromolecules
    Dennis Svatunek
    • Sep 27, 2019
    • 1 min

    New article on tetrazine modified nanoparticles published in Biomacromolecules

    Our paper together with the Zentel group at Johannes Gutenberg University Mainz is now available in Biomacromolecules. Great work by...
    5 views0 comments
    Dennis Svatunek
    • Sep 14, 2019
    • 1 min

    New paper: Isonitrile-responsive and Bioorthogonally Removable Tetrazine Protecting Groups

    Together with the Franzini group we unraveled the mechanism of an accelerated release reaction in an isonitrile/tetrazine click to...
    5 views0 comments
    Dennis Svatunek
    • Jul 8, 2019
    • 1 min

    autoDIAS published in JCC

    Our paper about our python tool for an automated Distortion/Interaction Activation Strain analysis is online in the Journal of...
    20 views0 comments
    Dennis Svatunek
    • Jul 5, 2019
    • 1 min

    Talk at Austrian Chemistry Days 2019

    I will present research about bioorthogonal isonitrile/tetrazine reactions at the Österreichische Chemietage (Austrian Chemistry days) in...
    13 views0 comments
    Dennis Svatunek
    • Jul 1, 2019
    • 1 min

    NOS 2019 - poster presentation

    Last week I attended NOS2019 at Indiana University in Bloomington, Indiana. A great meeting for networking and learning about science. I...
    1 view0 comments
    Dennis Svatunek
    • Jun 20, 2019
    • 1 min

    Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonit

    Our paper together with the Franzini group "Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with...
    9 views0 comments
    Cover Picture in Angewandte Chemie
    Dennis Svatunek
    • Jun 8, 2019
    • 1 min

    Cover Picture in Angewandte Chemie

    Our article "Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles" is featured as a...
    23 views0 comments
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    dennis.svatunek@gmail.com

    Dennis Svatunek

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