New paper with the Boger group on 1,2,3-Triazine cycloadditions
Together with the Boger lab we recently published our work "Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and...
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Dennis Svatunek
- May 19, 2022
- 1 min
New JACS paper: Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the
Our paper on the reactivity of 2-pyridyl tetrazines is now open access in JACS: https://pubs.acs.org/doi/10.1021/jacs.2c01056
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Dennis Svatunek
- Sep 18, 2020
- 1 min
Creating 2 Billion virtual compounds - new paper with the Harran group
Together with the Harran group (UCLA) we worked on a computational workflow to create a gigalibrary of composite peptidic macrocycles...
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Dennis Svatunek
- Jun 29, 2020
- 1 min
New paper in Polymer Chemistry: Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides
In this paper we describe the synthesis of tetrazine and trans-cyclooctene modified polypept(o)ides and their bioorthogonal reactivity....
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![New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w](https://static.wixstatic.com/media/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png/v1/fill/w_454,h_266,fp_0.50_0.50,q_95,enc_auto/cc1c9a_ec1c3e2f3f30454896281f9df6799773~mv2.png)
Dennis Svatunek
- Feb 14, 2020
- 1 min
New paper about the "Concerted [4+2] and Stepwise (2+2) Cycloadditions of Tetrafluoroethylene w
We published a mechanistic study of the 2+2 and 4+2 cycloadditions between tetrafluorotheylene and butadiene. Read it here! (open access)
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Dennis Svatunek
- Jan 18, 2020
- 1 min
New paper: Live Monitoring of Strain‐Promoted Azide Alkyne Cycloadditions in Complex Reaction Enviro
We describe how ATR-IR can be used to follow strain-promoted azide alkyne cycloadditions even in biological solvent. Read this open...
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Dennis Svatunek
- Dec 11, 2019
- 1 min
New ACS nano paper: Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of
We demonstrate that PeptoBrushes can be used for pretargeted nuclear imaging. These PeptoBrushes also show unusual bioorthogonal...
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Dennis Svatunek
- Sep 27, 2019
- 1 min
New article on new glycosyl donors for diastereoselective glycosylations published in Chemical Commu
This paper includes work I performed in my bachelor thesis. Great work by all authors! Link to paper (open access)
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Dennis Svatunek
- Sep 27, 2019
- 1 min
New article on tetrazine modified nanoparticles published in Biomacromolecules
Our paper together with the Zentel group at Johannes Gutenberg University Mainz is now available in Biomacromolecules. Great work by...
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Dennis Svatunek
- Sep 14, 2019
- 1 min
New paper: Isonitrile-responsive and Bioorthogonally Removable Tetrazine Protecting Groups
Together with the Franzini group we unraveled the mechanism of an accelerated release reaction in an isonitrile/tetrazine click to...
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Dennis Svatunek
- Jul 8, 2019
- 1 min
autoDIAS published in JCC
Our paper about our python tool for an automated Distortion/Interaction Activation Strain analysis is online in the Journal of...
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Dennis Svatunek
- Jun 20, 2019
- 1 min
Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonit
Our paper together with the Franzini group "Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with...
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Dennis Svatunek
- Jun 8, 2019
- 1 min
Cover Picture in Angewandte Chemie
Our article "Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles" is featured as a...
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